Patient # 2 was a 67 year old Caucasian female with a history of moderate to sever chronic obstructive pulmonary disease. She was admitted to the hospital for a presumed COPD exacerbation and treated with systemic steroids and antibiotics. Her initial chest radiograph was normal. Over the next 4 weeks she was persistently febrile and repeat chest radiography revealed bilateral patchy opacities. A subsequent CT scan revealed multiple nodular opacities with cavitations disrupting several of her pulmonary bullae. Bronchoscopy was performed and she was diagnosed with pulmonary Aspergillus fumigatas. Her steroids were tapered rapidly and Amphotericin B was begun. During her subsequent therapy she noted significant improvement in her dyspnea. Table 2 presents the results of pulmonary function testing and arterial blood gas sampling prior to hospitalization (pre-bullectomy) and following treatment for her Aspergillus infection (post-bullectomy).